Cerebral lactic alkalosis persisting months after birth asphyxia

Birth asphyxia and cerebral palsy

resection,2 and in Britain we may well be dealing mostly with patients whose disease has infiltrated into surrounding tissue. The early disease in Japan may be different from that in Britain because the survival in Japanese patients (95%) is so much better than that in British patients (70%) that it cannot be explained purely on the basis of removing more affected nodes-and even RI resection in...

Brain alkalosis causes birth asphyxia seizures, suggesting therapeutic strategy.

OBJECTIVE The mechanisms whereby birth asphyxia leads to generation of seizures remain unidentified. To study the possible role of brain pH changes, we used a rodent model that mimics the alterations in systemic CO(2) and O(2) levels during and after intrapartum birth asphyxia. METHODS Neonatal rat pups were exposed for 1 hour to hypercapnia (20% CO(2) in the inhaled gas), hypoxia (9% O(2)), ...

Quality of survival after severe birth asphyxia.

Thirty-one children who survived severe birth asphyxia defined by a 1-minute Apgar score of 0, or a 5-minute Apgar score of less than 4, have been seen at age 5 to 10 years for neurological and psychological assessment. Their progress has been compared with that of controls matched for sex, birthweight, gestational age, and social class. 29(93%) of the 31 asphyxiated group and all the controls ...

Thiopentone induced coma after severe birth asphyxia.

The aim of this study was to determine the feasibility of inducing a prolonged coma in severely asphyxiated newborn babies by the infusion of high dose thiopentone. In six severely asphyxiated babies the electroencephalograph (EEG) and blood pressure were monitored continuously. Thiopentone was infused at a rate sufficient to suppress completely the EEG providing the mean blood pressure remaine...

Birth asphyxia.